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All about aging signs and symptoms of aging theories of aging anti-aging treatment and prevention anti-aging diet anti-aging hormones anti-aging products anti-aging medicine anti-aging skin care anti-aging tips human growth hormone human growth hormone (HGH) and anti-aging DHEA (Dehydroepiandrosterone) and anti-aging

Anti-aging products, supplements and nutrients

Supplements are a critical component for health and disease prevention. Supplementing your diet with vitamins, minerals and herbs will significantly increase your life span. These agents to diet cannot replace proper nutrition, but aid and abet a healthy life extension. Not all nutrients are anti-aging supplements per se. Anti-aging supplements address and prevent any possible deterioration in the cells that may accelerate the aging process. As the human body ages, certain things happen. Muscle mass decreases, bones become brittle and our bodies do not fight disease and injury as well as before. Hearing, eyesight, reflexes, as well as many other bodily functions may also be effected. Some foods, however, hold solutions to slowing the aging of our bodies and maintaining a healthy longer lifespan.

As we age, the nutritional needs of our bodies change. Many times, vitamin and mineral deficiencies are misdiagnosed as serious illnesses. In youth, our digestive systems digest and utilize nutrients readily. During aging, the digestive and absorption processes do not function well as before. These problems can be greatly reduced with the aid of nutritional supplements.

Human Growth Hormone

Human growth hormone (or hGH) is a polypeptide that is synthetised by somatotroph cells of the anterior lobe of pituitary gland. The genes for human growth hormone are localized in the q22-24 region of 17 chromosome and they are closely related to human chorionic sommatotropin (hCS) genes. The hormone is built of single polypeptide chain of 191 amino acid residues and has molecular weight of about 22,000. Despite marked structural similarities between growth hormone from different species only human and primate growth hormone is active in humans. Human growth hormone helps maintain the immune system and builds youthful muscle power and strength. Growth hormone levels decline progressively with advancing age. Scientists have demonstrated that restoring youthful levels of growth hormone via regular injections can rejuvenate aging men and women.

DHEA (dehydroepiandrosterone)

DHEA (Dehydroepiandrosterone) is a steroid hormone produced in the adrenal gland early in the day. It is the most abundant steroid in the bloodstream and is present at even higher levels in brain tissue. DHEA levels are known to decline with age. (see chart above). It appears in the blood steam by age seven and reaches its peak between 25 and 30; gradually, falling as much as 90% by age 60. Declining DHEA and the corresponding decline in dependent hormones has been linked to the loss of muscle tissue and stamina, fatigue, increased body fat, a decline in sex drive and an increased susceptibility to disease. Although the specific mechanisms of action for DHEA are only partially understood, supplemental DHEA has been shown to have a positive influence on markers that define aging and obesity.


Testosterone, thought of as a male hormone, is actually produced by both men and women, though in larger quantities in men. Supplements are available by prescription for men who do not produce enough of the hormone naturally. Men who might need supplements are those whose pituitary or testes glands have been damaged by infection or tumors. For these men, the supplements are clearly beneficial by restoring normal levels of the hormone. On the other hand, too much testosterone is clearly harmful, as demonstrated by athletes who have damaged their health through steroid (i.e. testosterone) supplements. Testosterone replacement therapy (TRT) is as powerful an anti-aging effect as estrogen or progesterone replacement in women. Many benefits are associated with taking testosterone such as renewed strength, improved balance, raised blood cell count, increased libido, lowered LDL and cholesterol. It also stems the loss of bone mass in men. However, TRT is not without side effects. These are known to be: higher levels of PSA (prostrate specific Antigen) and a rise in hematocrit.


Estrogen represents an entire family of female related hormones. For one it reduces heart diseases and controls LDL cholesterol. It is often used to prevent hot flashes and mood swings associated with menopause. Other benefits include: the preventing of heart disease and rapid decline of bone density after menopause, the improvement of body composition, protecting against Alzheimer and stimulating GH. Estrogen replacement therapy, available by prescription, can counteract these increased risks for certain women. Early studies also suggest that estrogen supplements might delay the onset of Alzheimer's disease, though this is preliminary. On the other hand, estrogen supplements might contribute to increased risk of blood clots, uterine cancer, and possibly breast cancer.


Progesterone - functions in many capacities. It is often taken to counter the effects of estrogen, normally used by women during postmenopausal. It also goes by the prescription . Natural progesterone is available as well and is known to have far fewer side effects. Progesterone has many functions. First, it is both a precursors to other adrenal hormones and a GH stimulant as well. It likewise promotes lipolysis (breakdown of fat) and protects against endometrial cancer. It is known to eliminate the risk of endometrial cancer when given with estrogen for 10 or more days per cycle. Lastly, progesterone normalizes levels of blood sugar, zinc and copper. Progesterone stimulate the walls of the uterus to prepare it for implantation of the fertilized ovum. If pregnancy occurs, progesterone inhibits ovulation (by suppressing FSH & LH) and promotes uterine development until the placenta becomes more mature. (Progesterone is so-named because it promotes gestation, ie, the growth of offspring in the womb).


Melatonin is a hormone produced by the pineal gland, which is located beneath the brain. Melatonin is a highly potent antioxidant, which has been described as the pacemaker of the aging clock in humans. Melatonin's main use has been to regulate sleep and circadian rhythms and allow the individual to feel more refreshed and alert the following day. As melatonin is directly involved with sleep regulation, the supplement's use in the treatment of age-related sleep disorders, jet lag or shift work is impressive.

Acetyl-L-Carnitine (ALC)

Acetyl-L-carnitine plays a key role in maintaining acetylcholine level and neuroprotective function during aging. Acetyl-L-carnitine is a naturally occurring compound that supports normal brain and nerve function during aging through various mechanisms. These include its actions on acetylcholine synthesis, cellular membrane stability. nerve growth factor production, and cerebral blood flow. ALC may be able to slow aging comes from evidence that ALC improves mitochondrial function in several ways. Mitochondria are the power plants of the cells, where energy for all life processes is generated. Scientists have speculated that the decline in mitochondrial function may be a cause of aging in humans.

Coenzyme Q10

Coenzme Q10 is present in all body cells, with the heart and liver containing the greatest amount. A major function of Coenzyme Q10 is to act as the catalyst in the production of energy at the cellular level. Research shows that there is a decline of Coenzyme Q10 levels with aging and that the decline of Coenzyme Q10 over time might be intimately linked to fundamental aging mechanisms and play a causative role in aging itself.

Alpha-Lipoic Acid

Alpha Lipoic Acid is a powerful antioxidant and actually regenerates free radicals back to their protective antioxidant state. Many of the benefits of Alpha Lipoic Acid is from its' antioxidant properties and the associated ability to fight free radicals and regenerate other antioxidants. Unlike vitamins C and E which only work in water and fat, ALA neutralizes free radicals in both fat and water. When antioxidants such as C and E eliminate free radicals, they lose electrons. ALA actually helps restore those lost electrons so C and E can go on working. Alpha lipoic acid can reduce glycation damage due to excess glucose in the blood, which may be involved in aging, and that it can improve patients with diabetes, which has been described as an accelerated form of aging.


Cysteine is a powerful free radical destroyer by itself, but works best when vitamin E and selenium are present. It helps detoxify and protect the body from radiation damage, so it is often used in conjunction with chemotherapy and radiation cancer treatments. Cysteine is a precursor to the liver detoxifying and antioxidant amino acid glutathione. This functionality provides an anti-aging effect on the body—even reducing the accumulation of age spots. Another impressive function is the break down of mucus in the respiratory tract which can help in bronchitis, emphysema, and tuberculosis.

NADH (Nicotinamide Adenine Dinucleotide)

NADH or Nicotinamide Adenine Dinucleotide is a coenzyme - the active part of a vitamin - in this case the active part of vitamin B3. NADH is involved in the process of creating ATP (energy). Look at the chart to see how NADH is involved in the role of producing ATP. NADH is a valuable tool in the fight against aging especially age-related mental decline. NADH can energize aging or degenerative brain cells. Also, its ability as an antioxidant can protect the brain from cellular damage due to free radicals.


Lycopene is a member (along with beta-carotene) of a family of plant pigments called carotenoids. Lycopene may be the best free radical scavenger among carotens - it is at least twice as effective an antioxidant as beta carotene. In addition to protecting cells from free radical damage, lycopene may produce its beneficial effect by other means, such as improving the function of cell-to-cell junctions and some aspects of cell metabolism. Lycopene is the best antiaging candidate of this class of compounds because it is the most efficient quencher of an especially dangerous free radical called singlet oxygen. Equally important is the fact that lycopene is regenerated after quenching singlet oxygen, and can then detoxify dangerous molecules without being destroyed. Lycopene levels drop off with age, even if we continue eating the fruits and vegetables that contain it.

Vitamin E

Vitamin E is a fat-soluble nutrient that that body stores in the liver, and fat tissue. Vitamin E is a potent antioxidant. Antioxidants neutralize free radicals, which are highly reactive chemical substances that can cause cellular damage if left unchecked, leading to premature aging and disease. Vitamin E is the major fat-soluble compound that protects our cell membranes against oxidative damage. It can break the self-perpetuating chain of oxidative reactions in unsaturated fatty acids in membranes. Vitamin E also helps maintain the antioxidant activity of selenium, and works with this trace mineral to help boost immune function.

Vitamin B5 (Pantothenic Acid)

As with the other B Vitamins, Pantothenic Acid is a crucial nutrient for energy metabolism. It also makes brain neurotransmitters and natural body steroid hormones. Deficiency of pantothenic acid in rats causes highly notable failure of cartilage growth and lesions like the lesions in osteoarthritis. Vitamin B5 is central to the energy-yielding oxidation of glucose products and it also enhances the ability to withstand stress. Vitamin B5 fights aging because it is a constituent of coenzyme A, which is involved in many chemical reactions essential to life, including detoxification of dangerous substances.

Vitamin B6 (Pyridoxine)

Vitamin B6 functions in the formation of body proteins and amino acid metabolism, chemical transmitters in the nervous system, red blood cells, and prostaglandins. Vitamin B6 (Pyridoxine) is vital for metabolizing the amino acids tyrosine and phenylalanine. It is an essential co-factor (along with vitamin B12 and folic acid) in the body’s fight against elevated homocysteine levels, which are linked to arteriosclerosis, heart disease, and stroke. Vitamin B6 plays an important role in many life processes. It is needed for the metabolism of amino acids such as tyrosine and phenylalanine, and is an essential cofactor (along with vitamin B6 and folic acid) in the body's defense against elevated homocysteine levels, which have been linked to arteriosclerosis, heart disease and stroke.

Vitamin C (Ascorbic Acid)

Vitamin C has been shown to inhibit the deposit and growth of atherosclerosis on artery walls, directly protect the heart muscle from infection and free radical damage, delay or prevent cataract formation, help prevent cancer and infection in skin. Vitamin C helps virtually every cell in body to resist aging. Vitamin C is more effective than vitamin E, lutein, or zeaxanthin at preventing macular degeneration. It is important to note that these supplements are effective in preventing macular degeneration, not reversing it -- another illustration of the notion that prevention is the key to lasting health.

Gingko Biloba

Gingko biloba is considered the "brain herb" in traditional Chinese medicine. Along with being a powerful antioxidant and a powerful free radical-scavenger, this herb protects the integrity of cells. Numerous studies have revealed its many health benefits such as nerve function, vascular integrity, cerebral vascular function (helps with short-term memory loss, vertigo, headaches, ringing in the ears, lack of vigilance, and depression), Alzheimer’s disease, senile macular degeneration, impotence, and more.


Selenium is an essential mineral nutrient for both humans and animals. Selenium is said to help preserve elasticity in body tissues, slow the aging process, improve the flow of oxygen to the heart, and help prevent abnormal blood clotting. Selenium is an antioxidant, a compound that blocks the action of activated oxygen molecules, known as free radicals, that can damage cells. Selenium may stimulate the formation of antibodies (proteins that help fight invading microorganisms) in response to vaccines. Selenium may also play a role in normal growth, development, and fertility.

DMAE (Dimethylaminoethanol)

DMAE, or dimethylaminoethanol, is a compound found in high levels in anchovies and sardines. Small amounts of it are also naturally produced in the human brain. Because it steps up production of brain chemicals essential for short-term memory, concentration, and learning capacity, DMAE may aid in the treatment of ADHD and other disorders affecting the brain and central nervous system. The combination of DMAE and the herb gingko has become popular choice for helping mild memory problems associated with aging.


Vinpocetine is a vasodilator, in other words it improves brain blood flow with a unique non-steal affect, that is to say it only affects areas that need to be improved. Accordingly, by improving brain blood flow, vinpocetine has been shown to help improve hearing (particularly tinnitus), eyesight and even alleviate the problems involved with menopause. Vinpocetin is another nutrient that may be helpful with mild memory problems associated with aging and promoting healthy blood flow.

Chromium Picolinate

Chromium picolinate promotes efficient function of the hormone insulin. Good insulin activity is important for hunger control, for stimulating metabolism, and for building and retaining muscle and vital organ tissue. The ability of chromium picolinate to retain muscle is important to dieters, since up to 30% of the weight lost on most diets is muscle tissue. Chromium Polynicotinate is actually a family of niacin-bound chromium compounds. Niacin-bound chromium strongly potentiates insulin - chromium's most vital function - while chromium picolinate is less effective comparatively speaking.

More information on anti-aging

What is aging? - Aging is a syndrome of changes that are deleterious, progressive, universal and thus far irreversible. Aging is usually understood to include reductions in reproductive capacity.
What're signs and symptoms of aging? - There is a reduction of the thymus gland to 5-10% of its original mass by age 50. Levels of antibodies increase with aging. One third of men and half of women over 65 report some form of arthritis.
Theories of aging - Aging is the process of growing older and includes changes in both biology and psychology. Theories that explain aging can generally be divided between the programmed and error theories of aging.
What is the anti-aging treatment and prevention? - A healthy lifestyle, caloric restriction with adequate nutrution (CRAN), and perhaps even supplements can do no more than slow the aging process or extend mean lifespan.
Anti-aging diets - Caloric restriction (CR) - Caloric restriction (CR) is the practice of limiting dietary energy intake to improve health and retard aging. In human subjects, CR is known to slow the signs of aging.
Anti-aging hormones - Hormones are chemicals released into the bloodstream from glands. The hormones DHEA, melatonin, thyroid, and somatotropin (GH) decline with age.
Anti-aging supplements and nutrients - Supplements are a critical component for health and disease prevention. Anti-aging supplements address and prevent any possible deterioration in the cells that may accelerate the aging process.
Anti-aging medicine - Anti-aging medicine incorporates many of the principals of ortho-molecular medicine to retard aging and rejuvenate the body.
Anti-aging skin care - The largest growth area in cosmetic facial treatment is related to aging. People are living longer and healthier and want their appearance to reflect their vital state of mind and health.
Anti-aging tips - The single best thing you can do for your health and longevity is quit smoking. Drink only in moderation. Find a doctor who specializes in geriatrics or anti-aging.
Human growth hormone (HGH) and anti-aging - Human growth hormone (HGH) is produced in the pituitary gland of humans, and the hormone is secreted throughout a persons lifetime.
DHEA (Dehydroepiandrosterone) and anti-aging - DHEA or dehydroepiandrosterone, is a natural sterone produced naturally in the body by the adrenal glands and is the sole precursor and regulator for the natural production of every steroid and sex hormone in the body.
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All information is intended for reference only. Please consult your physician for accurate medical advices and treatment. Copyright 2005,, all rights reserved. Last update: July 18, 2005